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Noncompetitive Inhibition Is Best Described as

Noncompetitive inhibitors are important in feedback inhibition in which the amount of product produced by a series of reactions is carefully controlled. Activity is mediated predominately by noncompetitive inhibition of HIV-1 reverse transcriptase.


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The 9095 inhibitory concentration of efavirenz is approximately 1725 nmol l 1.

. Learn vocabulary terms and more with flashcards games and other study tools. Start studying Biology Chapter 8. The experimental work described here was developed for and tested in a 2nd-year undergraduate laboratory course designed primarily to provide students with laboratory.

The final product in a series of reactions acts as a noncompetitive inhibitor of the initial enzyme. HIV-2 reverse transcriptase and human cellular DNA polymerases α β γ and δ are not inhibited by efavirenz. For enzyme inhibition studies alkaline phosphatase is competitively inhibited by both of its reaction products and is uncompetitively inhibited by the L-isomer of the amino acid phenylalanine.

Simple enzymes consist entirely of one or more amino acid chains.


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